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Fructosyl-peptide Oxidase (FPOX) egosipụtara
  • Fructosyl-peptide oxidase (FPOX)

Fructosyl-peptide oxidase (FPOX)


Nọmba EC:1.5.3

Ngwugwu: 1ku,10ku,50ku

Nkọwa ngwaahịa

Nkọwa

Enzyme ahụ bara uru maka mkpebi nke fructosyl-peptide na fructosyl-L-amino acid.

Ọdịdị Chemical

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Ụkpụrụ mmeghachi omume

Fructosyl-peptide + H2O + O2→ Peptide + Glucosone + H2O2

Nkọwapụta

Nnwale ihe Nkọwapụta
Nkọwa Ọcha amorphous ntụ ntụ, lyophilized
Ihe omume ≥4U/mg
Ịdị ọcha (SDS-PAGE) ≥90%
Catalase ≤0.01%
ATPase ≤0.005%
Glucose oxidase ≤0.03%
Cholesterol oxidase ≤0.003%

Ụgbọ njem na nchekwa

Ụgbọ njem: Ambient

Nchekwa:Na-echekwa na -20°C (Ogologo oge), 2-8°C (obere oge)

Nnwale akwadoroNdụ:Afọ 2

Akụkọ mmepe

Otu n'ime ndenye aha eji achọpụta ọrịa shuga bụ haemoglobin glycated (HbA1c).Ntụle HbA1c na-eji enzymes dabara adaba maka ịhazi ọnụ ọgụgụ dị ukwuu nke ụdị, ọ dịkwa ọnụ ahịa nke ọma.Dị ka ndị dị otú a, enwere ogologo oge oku siri ike sitere n'aka ndị na-ahụ maka ahụike maka mmepe nke nyocha nke enzyme dị otú ahụ.Ya mere, anyị mepụtara nyocha ọhụrụ site na iji "usoro dipeptide".Kpọmkwem, anyị chọpụtara "Fructosyl-peptide Oxidase" (FPOX) nke enwere ike iji dị ka enzyme maka nyocha a.Nke a mere ka anyị nwee ihe ịga nke ọma n'inweta nke mbụ n'ụwa site n'imepụta eziokwu nke nyocha enzyme HbA1c."Usoro dipeptide" a na-eji Protease (Proteolytic enzyme) imebi HbA1c n'ime ọbara, wee tụọ ọkwa nke dipeptides saccharified nke emepụtara site na iji FPOX.Usoro a nwetara nnabata dị mma nke ukwuu n'ihi uru ya dị mfe, dị ọnụ ala na ngwa ngwa, yana reagent HbA1c site na iji FPOX abiala ka ejiri ya mee ihe n'ụwa niile.


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