Methylprednisolone (83-43-2)
Nkọwa ngwaahịa
● Methylprednisolone, ihe na-emepụta ihe, bụ glucocorticoid na-eme ihe na-eme ihe na-enwe mmetụta siri ike na-egbochi mkpali.
● Methylprednisolone na-eji maka ọgwụgwọ mberede nke ọrịa ndị dị oke egwu nakwa maka ọrịa endocrine, ọrịa rheumatic, ọrịa collagenous, ọrịa anụ ahụ, mmeghachi ahụ nfụkasị ahụ, ọrịa anya, ọrịa eriri afọ, ọrịa ọbara, leukemia, ujo, ụbụrụ ụbụrụ, polyneuritis, myelitis na mgbochi nke. vomiting nke chemotherapy kpatara.Ka ọ dị ugbu a, a na-ejikarị ya eme ihe na ụlọ ọgwụ maka ịmịnye akụkụ ahụ.
● Ogo Ogo: USP
| Ngwaahịa | Methylprednisolone | Ụbọchị nrụpụta | 2017.05.15 |
| Ogbe Mba. | NXEMP 170601 | Ụbọchị mkpesa | 2017.06.14 |
| Usoro | EP 8.0 | Ụbọchị nyochagharị | 2019.05.15 |
| Nkọwapụta | Nsonaazụ | ||
| Njirimara | A na-acha ọcha ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ ọcha, ntụ ntụ kristal | White crystalline ntụ ntụ | |
| njirimara | A(IR), B(HPLC) | Dabara | |
| Ntụgharị anya pụrụ iche | +97.0° 〜+103.0° | + 99.7 Celsius | |
| Ihe ndị metụtara ya | Mkpokọta adịghị ọcha <2.0% adịghị ọcha A <0.3% adịghị ọcha B <0.2% adịghị ọcha C <0.15% adịghị ọcha D (D isomerl na D isomer2) <0.5% adịghị ọcha E <0.15% adịghị ọcha H <0.2% Nchikota nke adịghị ọcha G na m <0.3% Ihe adịghị ọcha na-akọwapụtaghị <0.10% | Mkpokọta: 0.14% <0.05%0.08%<0.05%D isomerl :<0.05%D isomer2:<0.05%<0.05%<0.05%<0.05% kwadoro | |
| Ọnwụ na ihicha | <1.0% | 0.16% | |
| Nyocha | 97.0% ~ 102.0% | 100.8% | |
| Ihe mgbaze fọdụrụnụ | Dichloromethane <600ppmMethanol <3000ppm | 73ppm249ppm | |
| Nha ogbe | 72.3 n'arọ | ||
| Ọnụọgụ | 72.3 n'arọ | ||
| Mmechi | Ngwaahịa a dị n'elu kwekọrọ na EP8.0 | ||
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