Doxycycline Hyclate (24390-14-5)
Nkọwa ngwaahịa
● Doxycycline Hcl bụ antibacterial spectrum dị nso na Tetracycline na Terramycin, ma ọ na-enwe mmetụta ka mma, na-enwe mmetụta nke Staphylococcus Aureus nke tetracycline na-eguzogide ọgwụ, oxytetracycline, na-adịgide adịgide. ọrịa nku ume, nnukwu tonsillitis, mycoplasma oyi baa, urinary tract ọrịa, ọbara nsi, bacillary ọnyụnyụ ọbara, nnukwu lymphadenitis, wdg. Ọ bụ nnọọ ewu ewu na Nephropathy na-arịa ọrịa n'ihi na ya doro anya nsi maka akụrụ.
● Doxycycline Hyclate bụ ụdị nnu hyclate nke doxycycline, ọgwụ nje tetracycline sịntetịt, nke na-egosipụta ọrụ mgbochi nje.Doxycycline hyclate na-ejikọta reversibly na 30S ribosomal subunit, ikekwe na 50S ribosomal subunit, si otú ahụ na-egbochi njikọ nke aminoacyl-tRNA na mRNA-ribosome complex.Nke a na-eduga na mgbochi nke njikọ protein.Na mgbakwunye, onye nnọchi anya a egosipụtala mgbochi nke ọrụ collagenase.
Ngwa
A na-eji Doxycycline Hyclate agwọ ọrịa dị iche iche nke nje bacteria, gụnyere ndị na-ebute ihe otutu.A na-ejikwa Doxycycline Hyclate egbochi ịba.A maara Doxycycline Hyclate dị ka ọgwụ nje tetracycline.Ọ na-arụ ọrụ site n'ịkwụsị uto nke nje bacteria. Ọgwụ nje a na-agwọ naanị ọrịa nje.
| Ihe | Nkọwapụta | Nsonaazụ |
| Ọdịdị | Odo kristal ntụ ntụ | Dabara |
| njirimara | TLC | Dabara |
| sulfuric acid mmeghachi omume agba odo na-etolite | Dabara | |
| ọ na-enye mmeghachi omume nke chlorides | Dabara | |
| PH | 2.0-3.0 | 2.3 |
| Ntinye aka nkenke | na 349nm e(1%) 300-355 | 320 |
| Ntụgharị anya pụrụ iche | -105 ~ -120 ° | -110° |
| Ọla dị arọ: | ≤50ppm | <20pm |
| adịghị ọcha na-ebu ọkụ | na 490nm ≤0.07 | 0.03 |
| Ihe ndị metụtara ya | 6-epidoxycycline ≤2.0% metacycline ≤2.0% 4-epidoxycycline ≤0.5% (ep5) 4-epi-6-epidoxycycline ≤0.5% (ep5) oxytetracycline ≤0.5% (ep5) adịghị ọcha ọ bụla ọzọ ≤0.5% Achọpụtaghị adịghị ọcha ≤0.1% (ep5) | 1.6% 0.1% Ahụghị Ahụghị Ahụghị Ahụghị Ahụghị |
| Ethanol | 4.3 ~ 6.0% (m/m) | 4.5% |
| Sulfated uyi | ≤0.4% | 0.05% |
| Mmiri | 1.4-2.8% | 1.8% |
| Nyocha | 95.0 ~ 102.0% (c22h25cln2o8) dabere na anhydrous, ihe na-enweghị ethanol | 98.6% |
| Mmechi | Dakọtara na USP32 | |
